منابع مشابه
Drug-induced long QT syndrome.
The drug-induced long QT syndrome is a distinct clinical entity that has evolved from an electrophysiologic curiosity to a centerpiece in drug regulation and development. This evolution reflects an increasing recognition that a rare adverse drug effect can profoundly upset the balance between benefit and risk that goes into the prescription of a drug by an individual practitioner as well as the...
متن کاملImpact of Drug Induced Long QT Syndrome: A Systematic Review
Background Drug induced long QT syndrome is quite common in daily clinical practice but its impact is unknown. Methods PubMed and EMBASE databases (until May 2, 2017) were searched to identify studies reporting drug induced long QT syndrome and followed the PRISMA guidelines. The main outcomes measured in these studies were QTc prolongation, ventricular arrhythmias, torsade de pointes (TdP) a...
متن کاملDrug-induced long QT syndrome and Torsade de Pointes.
Several medications, including drugs prescribed for noncardiac indications, have been associated with a prolongation of the QT interval on the surface electrocardiogram. Under certain circumstances, this clinical manifestation may reflect an increased risk for patients presenting with a polymorphic ventricular tachycardia known as torsade de pointes. Drugs that prolong the QT interval belong to...
متن کاملCauses and management of drug-induced long QT syndrome.
Long QT syndrome (LQTS) is characterized by inherited or acquired prolonged QT interval on the surface electrocardiogram. This can lead to torsade de pointes ventricular tachycardia (TdP VT) and ventricular fibrillation. In the acquired form of the disease, medications from several classes can cause TdP VT or potentiate the electrocardiographic findings. These include class IA and III antiarrhy...
متن کاملArsenic-induced interstitial myocardial fibrosis reveals a new insight into drug-induced long QT syndrome.
AIMS Arsenic trioxide (ATO), an effective therapeutic agent for acute promyelocytic leukaemia, can cause sudden cardiac death due to long QT syndrome (LQTS). The present study was designed to determine whether ATO could induce cardiac fibrosis and explore whether cardiac fibroblasts (CFs) are involved in the development of LQTS by ATO. METHODS AND RESULTS ATO treatment of guinea pigs caused s...
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ژورنال
عنوان ژورنال: Arrhythmology
سال: 2020
ISSN: 2658-7327,1561-8641
DOI: 10.35336/va-2020-3-42-52